Description

Methyl 4-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Benzoate CAS NO 1381957-27-2 is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science who require reliable, high-quality boron reagents for precise carbon-carbon bond formation.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biphenyl or terphenyl scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of complex organic ligands and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Synthesis: Utilized for labeling and modifying biomolecules or creating fluorescent probes for diagnostic applications.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Methyl 4-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Benzoate
CAS No.	1381957-27-2
Molecular Formula	C20H23BO4
Molecular Weight	338.21 g/mol
Synonyms	Methyl 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)[1,1'-biphenyl]-4-carboxylate; 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-carboxylic Acid Methyl Ester; [1,1'-Biphenyl]-4-carboxylic Acid, 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-, Methyl Ester; Methyl 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzoate; Biphenyl-4-boronic Acid Pinacol Ester, 4'-Methoxycarbonyl Derivative; Pinacol [4'-(Methoxycarbonyl)biphenyl-4-yl]boronate
EINECS	Contact for details

Quality Control

Our Methyl 4-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee consistency and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.