Description

6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalene-2-Carbaldehyde is a high-value, multi-functional organic building block featuring both a formyl group and a protected boronic ester. This compound is essential for advanced organic synthesis, particularly in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection agents, leveraging the naphthalene core for enhanced biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for constructing complex organic semiconductors and host/emitter materials in display and lighting technologies.
• Ligand and Catalyst Development: The aldehyde and boronate functional groups allow for the synthesis of novel chelating ligands and organometallic catalysts.
• Polymer and Material Science: A monomer or cross-linking agent for producing specialty polymers with tailored optical or electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of fluorescent tags and molecular probes for diagnostic and research applications.

Basic Information

Product Name	6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalene-2-Carbaldehyde
CAS No.	1381940-44-8
Molecular Formula	C₁₇H₂₁BO₃
Molecular Weight	284.16 g/mol
Synonyms	2-Formyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-naphthaldehyde; 6-(Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene-2-carboxaldehyde; 2-Naphthalenecarboxaldehyde, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 6-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-naphthalenecarbaldehyde; Pinacol 6-Formyl-2-naphthylboronate; 6-Formyl-2-naphthylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is analyzed using advanced techniques including HPLC, NMR, and GC-MS to verify identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to cGMP principles for manufacturing critical intermediates, ensuring traceability and reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.