Description

[2-(2-Chloro-5-Methylphenoxy)-1-Cyclopropylethyl]Methylamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique phenoxy-cyclopropylmethylamine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), where its specific stereochemistry and functional groups enable targeted biological activity. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its phenoxy moiety for biological activity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and receptor interactions in biochemical research.
• Process Chemistry: Employed in route scouting and optimization for the scalable manufacturing of complex target molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	[2-(2-Chloro-5-Methylphenoxy)-1-Cyclopropylethyl]Methylamine
CAS No.	1379811-52-5
Molecular Formula	C13H18ClNO
Molecular Weight	239.74 g/mol
Synonyms	1-Cyclopropyl-2-[(2-chloro-5-methylphenoxy)methyl]ethylamine; N-Methyl-1-[2-(2-chloro-5-methylphenoxy)-1-cyclopropylethyl]amine; 2-(2-Chloro-5-methylphenoxy)-1-cyclopropylethanamine; (1-Cyclopropyl-2-{[2-chloro-5-methylphenyl]oxy}ethyl)methylamine; 1379811-52-5; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our [2-(2-Chloro-5-Methylphenoxy)-1-Cyclopropylethyl]Methylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformance to customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.