Description

4,4,5,5-Tetramethyl-2-(Naphthalen-2-Ylmethyl)-1,3,2-Dioxaborolane is a high-value, advanced boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in creating complex biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aromatic frameworks.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for constructing sophisticated organic semiconductors and emissive layer materials in display technologies.
• Polymer & Material Science: Enables the synthesis of functionalized monomers and polymers with tailored electronic or optical properties.
• Ligand & Catalyst Development: Acts as a starting material for creating novel bidentate or polydentate ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological pathways and target engagement.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(Naphthalen-2-Ylmethyl)-1,3,2-Dioxaborolane
CAS No.	1379610-55-5
Molecular Formula	C₁₉H₂₅BO₂
Molecular Weight	296.21 g/mol
Synonyms	2-(Naphthalen-2-Ylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(2-Naphthylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Methylnaphthalen-1-yl)boronic acid pinacol ester; 2-Naphthylmethylboronic acid pinacol ester; Naphthalen-2-ylmethylboronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-[(2-naphthalenyl)methyl]-4,4,5,5-tetramethyl-; Pinacol (2-naphthylmethyl)boronate
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(Naphthalen-2-Ylmethyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air or moisture must be avoided to maintain purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.