Description

(E)-3-Ethoxy-3-Oxoprop-1-Enylboronic Acid CAS NO 1379462-82-4 is a high-purity, advanced boronic acid derivative characterized by its α,β-unsaturated ester functionality. This compound is a critical building block in modern synthetic chemistry, enabling the formation of complex molecular architectures through reliable cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used to create novel active ingredients for crop protection products, leveraging its boronic acid group for selective bond formation.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Catalyst Ligand Development: Acts as a starting material for synthesizing sophisticated ligand systems used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex molecules on a commercial scale.

Basic Information

Product Name	(E)-3-Ethoxy-3-Oxoprop-1-Enylboronic Acid
CAS No.	1379462-82-4
Molecular Formula	C7H11BO4
Molecular Weight	169.97 g/mol
Synonyms	(E)-3-Ethoxy-3-oxoprop-1-en-1-ylboronic acid; trans-3-Ethoxy-3-oxoprop-1-enylboronic acid; (E)-2-Carbethoxyvinylboronic Acid; trans-2-Carbethoxyvinylboronic Acid; (E)-Ethyl 3-boronocrotonate; (E)-Ethyl (3-boronoacryl)ate; Boronic acid, B-[(1E)-3-ethoxy-3-oxo-1-propen-1-yl]-; (E)-1-Ethoxy-1-oxoprop-2-en-3-ylboronic acid
EINECS	Contact for details

Quality Control

Our (E)-3-Ethoxy-3-Oxoprop-1-Enylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.