Description

1-(2,6-Difluoro-4-Hydroxyphenyl)Ethanone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a ketone and a phenol group with fluorine substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorophenol or difluoroacetophenone core structure.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atoms can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals, where fluorinated aromatic units impart desirable thermal and chemical resistance.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(2,6-Difluoro-4-Hydroxyphenyl)Ethanone
CAS No.	1378820-19-9
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2',6'-Difluoro-4'-hydroxyacetophenone; 4'-Hydroxy-2',6'-difluoroacetophenone; 1-(2,6-Difluoro-4-hydroxyphenyl)ethan-1-one; 2,6-Difluoro-4-hydroxyacetophenone; 4-Acetyl-3,5-difluorophenol; Ethanone, 1-(2,6-difluoro-4-hydroxyphenyl)-
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluoro-4-Hydroxyphenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.