Description

1-(2,2,2-Trifluoroethyl)Pyrrolidine is a high-value fluorinated pyrrolidine derivative, serving as a crucial building block in advanced organic synthesis. Its unique structure, featuring a trifluoroethyl group, imparts significant electronic and steric properties, making it indispensable for modulating the pharmacokinetic profiles of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials that benefit from fluorine incorporation.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation or as a core structure in designing molecular probes and enzyme inhibitors.

Basic Information

Product Name	1-(2,2,2-Trifluoroethyl)Pyrrolidine
CAS No.	1378304-83-6
Molecular Formula	C6H10F3N
Molecular Weight	153.15 g/mol
Synonyms	N-(2,2,2-Trifluoroethyl)pyrrolidine; Pyrrolidine, 1-(2,2,2-trifluoroethyl)-; 2,2,2-Trifluoro-N-pyrrolidinoethane; 1-(Trifluoroethyl)pyrrolidine; N-Trifluoroethylpyrrolidine; 2,2,2-Trifluoroethylpyrrolidine
EINECS	Contact for details

Quality Control

Our 1-(2,2,2-Trifluoroethyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.