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(E)-Ethyl 3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate CAS NO 1377024-34-4


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CAS No.:1377024-34-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(E)-Ethyl 3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate is a high-purity boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where precise and reliable synthesis is paramount.

Application

  • Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides requiring specific aryl-boron functionalities.
  • Organic Light-Emitting Diodes (OLEDs): Building block for creating electron-transport materials and emissive layer components in display and lighting technologies.
  • Polymer & Material Science: Monomer for synthesizing specialty polymers with tailored properties for coatings, adhesives, and advanced composites.
  • Chemical Research & Development: Versatile reagent for academic and industrial R&D in medicinal chemistry and organic synthesis.
  • Liquid Crystal & Electronic Materials: Intermediate in the production of materials for liquid crystal displays (LCDs) and other electronic applications.

Basic Information

Product Name (E)-Ethyl 3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate
CAS No. 1377024-34-4
Molecular Formula C₁₉H₂₇BO₄
Molecular Weight 330.23 g/mol
Synonyms Ethyl (E)-3-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acrylate; 3-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acrylic acid ethyl ester; (E)-Ethyl 3-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propenoate; 2-(3-((E)-3-Ethoxy-3-oxoprop-1-en-1-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[3-[(1E)-3-ethoxy-3-oxo-1-propen-1-yl]phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
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Quality Control

Our (E)-Ethyl 3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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