Description

2-Ethoxy-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional pyridine-based boronic ester derivative, serving as a critical synthetic intermediate. Its core value lies in enabling efficient, selective cross-coupling reactions, which are fundamental to constructing complex molecular architectures in advanced research and development. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries, where it is used to introduce the pyridine moiety into target molecules. The CAS number for this compound is 1375303-03-9.

Application

This versatile boronic ester is a key building block in modern synthetic chemistry, primarily used in:

• Pharmaceutical Intermediates: Crucial for the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Development: Used in creating novel herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Material Science & OLED Research: Acts as a precursor for electron-transport materials and ligands in organic light-emitting diodes (OLEDs) and other electronic materials.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated pyridine-containing ligands for transition metal catalysis.
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules in drug discovery and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, functionalized pyridine cores.

Basic Information

Item	Details
Product Name	2-Ethoxy-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1375303-03-9
Molecular Formula	C15H24BNO3
Molecular Weight	277.17 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-ethoxy-3-methylpyridine; 2-Ethoxy-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Methyl-2-ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Ethoxy-3-methylpyridine-5-boronic acid pinacol ester; Pyridine-5-boronic acid, 2-ethoxy-3-methyl-, pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles as verified by HPLC, NMR, and other analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.