Description

2-(Benzyloxy)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a pivotal method for constructing complex molecular architectures. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Cross-Coupling Reactions: A dedicated boronic ester pinacol reagent for palladium-catalyzed Suzuki-Miyaura couplings, facilitating carbon-carbon bond formation under mild conditions.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis organizations (CSOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-(Benzyloxy)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1375302-97-8
Molecular Formula	C19H24BNO3
Molecular Weight	325.21 g/mol
Synonyms	3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(phenylmethoxy)pyridine; 2-(Benzyloxy)-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(benzyloxy)-3-methylpyridine; 2-Benzyloxy-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Boronic acid, B-[2-(benzyloxy)-3-methyl-5-pyridinyl]-, 1,3-propanediol cyclic ester; 3-Methyl-2-(phenylmethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our production of 2-(Benzyloxy)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR (1H, 13C, 11B), HPLC, and mass spectrometry. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) when opening the container for use to prevent degradation. For long-term storage, consider storing under an inert gas blanket.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.