Description

2-(2-Isopropyl-6-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial intermediate in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds under mild conditions. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to synthesize novel active ingredients and functional molecules. The CAS number for this compound is 1375301-93-1.

Application

This versatile boronic ester is a key building block in several high-value industrial and research applications:

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl and heterobiaryl scaffolds.
• Agrochemical Synthesis: Serves as a critical precursor in the development of new herbicides, fungicides, and insecticides.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of complex organic semiconductors and emissive layer materials for display technologies.
• Ligand and Catalyst Development: Acts as a precursor for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Polymer Chemistry: Utilized to introduce functional aryl groups into polymer backbones, modifying material properties.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic pathways and molecular architectures.

Basic Information

Product Name	2-(2-Isopropyl-6-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1375301-93-1
Molecular Formula	C₁₆H₂₅BO₂
Molecular Weight	260.18 g/mol
Synonyms	2-(2-Isopropyl-6-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Isopropyl-6-methylbenzeneboronic acid pinacol ester; (2-Isopropyl-6-methylphenyl)boronic acid pinacol ester; 2-Mesitylboronic acid pinacol ester (common misnomer); 2-(2-Isopropyl-6-methylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; B-(2-Isopropyl-6-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2-isopropyl-6-methylphenyl)boronate
EINECS	Contact for details

Quality Control

Our production of 2-(2-Isopropyl-6-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like NMR (¹H, ¹³C, ¹¹B), HPLC, and GC to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to meet the exacting standards required for GMP intermediates and research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.