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5-(n-Propoxy)Pyridine-3-Boronic Acid Pinacol Ester CAS NO 1375301-82-8


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CAS No.:1375301-82-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-(n-Propoxy)Pyridine-3-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
  • Agrochemical Research: Used in creating new candidate molecules for herbicides, fungicides, and insecticides with improved efficacy.
  • Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs and organic semiconductors.
  • Chemical Synthesis: Enables Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds under mild conditions, essential for constructing complex aromatic systems.
  • Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis and organometallic chemistry.
  • Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and discovery research in both academic and corporate laboratories.

Basic Information

Product Name 5-(n-Propoxy)Pyridine-3-Boronic Acid Pinacol Ester
CAS No. 1375301-82-8
Molecular Formula C₁₄H₂₂BNO₃
Molecular Weight 263.14 g/mol
Synonyms 5-Propoxypyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-propoxypyridine; 5-(Propoxy)-3-pyridineboronic acid pinacol ester; 5-n-Propoxy-3-pyridinylboronic acid pinacol ester; 3-Borono-5-propoxypyridine pinacol ester; 5-(n-Propoxy)-3-pyridylboronic acid pinacol ester; PINACOL 5-(PROPOXY)PYRIDIN-3-YLBORONATE
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Quality Control

Our 5-(n-Propoxy)Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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