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B-1H-Benzimidazol-2-Ylboronic Acid CAS NO 1375184-43-2


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CAS No.:1375184-43-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

B-1H-Benzimidazol-2-Ylboronic Acid is a high-purity boronic acid derivative featuring a benzimidazole scaffold, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional organic materials.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
  • Agrochemical Synthesis: Used in creating advanced fungicides, herbicides, and plant growth regulators with improved efficacy.
  • Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and luminescent materials.
  • Chemical Biology Probes: Facilitates the creation of boronic acid-based sensors and probes for detecting biological analytes.
  • Catalyst Ligand Development: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
  • Academic & Contract Research: Serves as a valuable reagent for method development and discovery chemistry in R&D laboratories.

Basic Information

Product Name B-1H-Benzimidazol-2-Ylboronic Acid
CAS No. 1375184-43-2
Molecular Formula C7H7BN2O2
Molecular Weight 161.96 g/mol
Synonyms 1H-Benzimidazol-2-ylboronic Acid; 2-Boronobenzimidazole; Benzimidazol-2-ylboronic Acid; 2-(Boronyl)-1H-benzimidazole; 1H-1,3-Benzodiazol-2-ylboronic Acid; B-(1H-Benzo[d]imidazol-2-yl)boronic Acid; 2-Borono-1H-benzimidazole
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Quality Control

Our B-1H-Benzimidazol-2-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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