Description

(2-Cyano-5-Methylphenyl)Boronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling reactions.
• Material Science Research: Building block for creating organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel bidentate ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	(2-Cyano-5-Methylphenyl)Boronic Acid
CAS No.	1375109-00-4
Molecular Formula	C8H8BNO2
Molecular Weight	160.97 g/mol
Synonyms	2-Cyano-5-methylbenzeneboronic acid; (2-Cyano-5-methylphenyl)boronic acid; 5-Methyl-2-cyanophenylboronic acid; 2-Cyano-5-methylphenylboronic acid; Boronic acid, B-(2-cyano-5-methylphenyl)-; 2-Cyanotoluene-5-boronic acid; 2-Methyl-4-boronobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of (2-Cyano-5-Methylphenyl)Boronic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and our rigorous analytical protocols include NMR, HPLC, and mass spectrometry for identity and purity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.