Description

5-Bromo-3-Methylisobenzofuran-1(3H)-One is a high-purity, specialized organic building block with a fused isobenzofuranone core structure. This compound is valued for its role as a versatile synthetic intermediate in advanced pharmaceutical and agrochemical research, enabling the construction of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides, leveraging its brominated heterocyclic structure.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced organic electronic materials and specialty polymers.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research at universities and CROs.

Basic Information

Product Name	5-Bromo-3-Methylisobenzofuran-1(3H)-One
CAS No.	1374574-45-4
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	5-Bromo-3-methyl-1(3H)-isobenzofuranone; 3-Methyl-5-bromophthalide; 5-Bromo-3-methylphthalide; 1(3H)-Isobenzofuranone, 5-bromo-3-methyl-; 1374574-45-4; 5-Bromo-3-methyl-3H-isobenzofuran-1-one
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Methylisobenzofuran-1(3H)-One is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for advanced intermediates, supporting our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.