Description

2-Amino-4-Bromo-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated and aminated structure, which enables precise molecular modifications in complex chemical pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, where the fluorine and bromine substituents enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals and organic semiconductors, due to its electron-withdrawing groups.
• Custom Synthesis and Contract Manufacturing: An essential substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Amino-4-Bromo-5-Fluorobenzoic Acid
CAS No.	1374208-42-0
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.03 g/mol
Synonyms	5-Fluoro-2-amino-4-bromobenzoic acid; 4-Bromo-5-fluoroanthranilic acid; 2-Amino-4-bromo-5-fluorobenzoic acid; Benzoic acid, 2-amino-4-bromo-5-fluoro-; 4-Bromo-5-fluoro-2-aminobenzoic acid; 5-Fluoro-4-bromoanthranilic acid; 2-Amino-5-fluoro-4-bromobenzoic acid
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-Bromo-5-Fluorobenzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.