Description

4-Butoxy-2,6-Difluorobenzylbromide is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in its functionalized benzyl bromide core, which is essential for constructing complex molecules through efficient alkylation and cross-coupling reactions. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and pesticides, leveraging the difluoro and alkoxy substituents.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated organic compounds used in electronic display technologies.
• Cross-Coupling Reactions: Acts as an electrophilic partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.
• Alkylating Agent: Utilized in organic synthesis to introduce the 4-butoxy-2,6-difluorobenzyl group into target molecules.

Basic Information

Product Name	4-Butoxy-2,6-Difluorobenzylbromide
CAS No.	1373921-06-2
Molecular Formula	C₁₁H₁₃BrF₂O
Molecular Weight	279.12 g/mol
Synonyms	1-(Bromomethyl)-4-butoxy-2,6-difluorobenzene; 2,6-Difluoro-4-butoxybenzyl Bromide; 4-Butoxy-2,6-difluorobenzyl Bromide; (4-Butoxy-2,6-difluorophenyl)methyl Bromide; α-Bromo-4-butoxy-2,6-difluorotoluene; 4-n-Butoxy-2,6-difluorobenzyl Bromide
EINECS	Contact for details

Quality Control

Our 4-Butoxy-2,6-Difluorobenzylbromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.