Description

2-Methyl-5-(Trifluoromethoxy)Acetophenone, 97% is a high-purity, fluorinated aromatic ketone building block essential for advanced organic synthesis. This compound is valued for its trifluoromethoxy (-OCF₃) substituent, which is a key pharmacophore known to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates. The 97% purity grade ensures reliable performance and consistent results in demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethoxy group contributes to improved biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require fluorinated aromatic components for specific electronic or surface properties.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis: A versatile reagent for Friedel-Crafts acylation and subsequent functional group transformations to create complex, multi-substituted aromatic systems.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethoxy)Acetophenone, 97%
CAS No.	1373920-71-8
Molecular Formula	C₁₀H₉F₃O₂
Molecular Weight	218.17 g/mol
Synonyms	1-[2-Methyl-5-(trifluoromethoxy)phenyl]ethanone; 2-Methyl-5-(trifluoromethoxy)acetophenone; 2'-Methyl-5'-(trifluoromethoxy)acetophenone; 1-(2-Methyl-5-(trifluoromethoxy)phenyl)ethan-1-one; α-Methyl-ω-(trifluoromethoxy)acetophenone (isomer specific); TFMO-Acetophenone derivative; CAS 1373920-71-8
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethoxy)Acetophenone, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification, GC for residual solvent analysis, and NMR/IR for structural confirmation, to ensure it meets the specified 97% minimum purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.