Description

1-(2-Pyridyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, catalyst development, and the synthesis of functional organic compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing heterocyclic cores prevalent in drug molecules.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific pyrazole-pyridine motifs.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other optoelectronic devices.
• Catalyst & Ligand Development: Employed in the synthesis of novel metal-organic complexes and catalysts for asymmetric synthesis and polymerization processes.
• Chemical Biology & Probe Synthesis: Utilized in the creation of molecular probes and bioconjugates for studying biological systems and diagnostic applications.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	1-(2-Pyridyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester
CAS No.	1373616-12-6
Molecular Formula	C14H18BN3O2
Molecular Weight	271.13 g/mol
Synonyms	1-(Pyridin-2-yl)-1H-pyrazole-4-boronic acid pinacol ester; 1-(2-Pyridinyl)-1H-pyrazole-4-boronic acid, pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-pyridinyl)-1H-pyrazole; 1-(2-Pyridyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; Pyrazole boronic ester derivative; 1-(2-Pyridyl)-1H-pyrazole-4-boronate pinacol ester
EINECS	Contact for details

Quality Control

Our 1-(2-Pyridyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.