Description

5-Bromo-1-(2-Fluorophenyl)-2-Pentanone is a specialized fluorinated and brominated ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated motifs into their target structures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorophenyl and bromoalkyl groups confer specific biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Precursor: Employed in the synthesis of monomers or functionalized polymers with unique electronic or surface properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme mechanisms or protein-ligand interactions due to its reactive halogen handle.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-1-(2-Fluorophenyl)-2-Pentanone
CAS No.	1373350-56-1
Molecular Formula	C11H12BrFO
Molecular Weight	259.12 g/mol
Synonyms	5-Bromo-1-(2-fluorophenyl)pentan-2-one; 2-Fluorophenyl 4-bromobutyl ketone; 1-(2-Fluorophenyl)-5-bromopentan-2-one; 4-Bromo-1-(2-fluorophenyl)butan-1-one (tautomeric form); α-Bromo-ω-fluoro valerophenone derivative; 2'-Fluoro-5-bromovalerophenone
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(2-Fluorophenyl)-2-Pentanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.