Description

1-Boc-5-Azaindole-2-Boronic Acid is a high-purity, advanced pharmaceutical intermediate and building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies developing novel therapeutics, where its unique structure enables the creation of targeted bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic acid functional group makes it an essential reagent for forming carbon-carbon bonds, a fundamental step in constructing complex organic molecules.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and the development of compound libraries for identifying new lead structures with potential biological activity.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Process Chemistry & Scale-up: Serves as a starting material or intermediate in the optimization and commercial-scale production of pharmaceutical compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical and biotechnology industries with custom synthesis and development services.

Basic Information

Product Name	1-Boc-5-Azaindole-2-Boronic Acid
CAS No.	1373273-47-2
Molecular Formula	C₁₂H₁₅BN₂O₄
Molecular Weight	262.07 g/mol
Synonyms	1-Boc-1H-pyrrolo[2,3-b]pyridine-2-boronic acid; 1-(tert-Butoxycarbonyl)-1H-pyrrolo[2,3-b]pyridine-2-boronic acid; 1H-Pyrrolo[2,3-b]pyridine-2-boronic acid, 1-[(1,1-dimethylethoxy)carbonyl]-; 1-Boc-7-azaindole-2-boronic acid; tert-Butyl 2-borono-1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 1-Boc-5-aza-indole-2-boronic acid; 1-Boc-1H-7-azaindole-2-boronic acid; 1-Boc-1H-pyrrolo[2,3-b]pyridine-2-boronic acid pinacol ester (related ester)
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Azaindole-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.