Description

B-(5-Methyl-3-Isoxazolyl)Boronic Acid CAS NO 1373229-27-6 is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for constructing heterocyclic scaffolds common in modern therapeutics.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a versatile organoboron partner for palladium-catalyzed coupling with aryl or vinyl halides, enabling the efficient synthesis of biaryl and other conjugated systems.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides that require specific isoxazole-containing structures.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is critical.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Item	Details
Product Name	B-(5-Methyl-3-Isoxazolyl)Boronic Acid
CAS No.	1373229-27-6
Molecular Formula	C6H8BNO3
Molecular Weight	152.95 g/mol
Synonyms	(5-Methylisoxazol-3-yl)boronic acid; 3-Borono-5-methylisoxazole; 5-Methyl-3-isoxazoleboronic acid; 5-Methylisoxazole-3-boronic acid; B-(5-Methyl-3-isoxazolyl)boronic acid; (5-Methyl-1,2-oxazol-3-yl)boronic acid; 3-(5-Methylisoxazolyl)boronic Acid
EINECS	Contact for details

Quality Control

Every batch of B-(5-Methyl-3-Isoxazolyl)Boronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR (¹H, ¹¹B, ¹³C), and mass spectrometry to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97%, with higher purity grades available. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.