Description

4-((5-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)-4,6-Dimethylpyridin-2-Yl)Oxy)-2-Methylbutan-2-Ol is a high-value, functionalized pyridine derivative containing a protected boronic ester moiety. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block for complex organic synthesis, particularly in medicinal chemistry. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the creation of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) for oncology, neurology, and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: The protected boronic ester group serves as a crucial reagent for forming carbon-carbon bonds, a fundamental step in constructing complex molecules.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and the development of targeted drug candidates, especially where the pyridine scaffold is pharmacologically relevant.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Potential precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its functionalized aromatic system.
• Process Chemistry & Scale-Up: Serves as a standardized intermediate for the reliable and scalable production of target molecules under GMP or non-GMP conditions.

Basic Information

Item	Details
Product Name	4-((5-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)-4,6-Dimethylpyridin-2-Yl)Oxy)-2-Methylbutan-2-Ol
CAS No.	1372195-90-8
Molecular Formula	C17H28BNO4
Molecular Weight	321.22 g/mol
Synonyms	2-Methyl-2-butanol, 4-[[5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-4,6-dimethyl-2-pyridinyl]oxy]-; 4-((5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-4,6-dimethylpyridin-2-yl)oxy)-2-methylbutan-2-ol; 2-Methyl-4-[5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-4,6-dimethylpyridin-2-yl]oxybutan-2-ol; PINACOL (4,6-DIMETHYL-5-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)PYRIDIN-2-YL) ETHER; Tert-butyl(5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-4,6-dimethylpyridin-2-yl) ether
EINECS	Contact for details

Quality Control

Our 4-((5-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)-4,6-Dimethylpyridin-2-Yl)Oxy)-2-Methylbutan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.