Description

1-Bromo-3-Chloro-5-(Propan-2-Yl)Benzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), enabling the introduction of specific halogen and alkyl substituents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where its substituted benzene core contributes to biological activity.
• Material Science: Serves as a precursor for organic electronic materials, including liquid crystals and charge-transport molecules for OLEDs.
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a building block for complex organic molecules in academic and industrial R&D.
• Ligand Preparation: Useful for synthesizing specialized phosphine or nitrogen-based ligands used in homogeneous catalysis.

Basic Information

Item	Details
Product Name	1-Bromo-3-Chloro-5-(Propan-2-Yl)Benzene
CAS No.	1369900-53-7
Molecular Formula	C9H10BrCl
Molecular Weight	233.53 g/mol
Synonyms	3-Bromo-5-Chlorocumene; 1-Bromo-3-chloro-5-isopropylbenzene; 5-Bromo-3-chlorocumene; (3-Bromo-5-chlorophenyl)propane; 2-Bromo-6-chloro-4-isopropylbenzene (alternate numbering); Cumene, 3-bromo-5-chloro-; 3-Chloro-5-bromocumene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-5-(Propan-2-Yl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.