Description

Benzene, 4-Chloro-2-Ethyl-1-Fluoro- CAS NO 1369889-05-3 is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring strategically placed chloro, ethyl, and fluoro substituents, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modification: Employed to introduce fluorine and chlorine functionalities into polymer chains, modifying characteristics like chemical resistance, weatherability, and surface energy.
• Organic Synthesis Reagent: Functions as a versatile reagent in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution reactions to construct complex aromatic systems.
• Chemical Research & Development: Essential for academic and industrial R&D focused on exploring new fluorination methodologies and the synthesis of structurally complex aromatic compounds.

Basic Information

Product Name	Benzene, 4-Chloro-2-Ethyl-1-Fluoro-
CAS No.	1369889-05-3
Molecular Formula	C8H8ClF
Molecular Weight	158.60 g/mol
Synonyms	1-Chloro-4-ethyl-2-fluorobenzene; 4-Chloro-2-ethyl-1-fluorobenzene; 2-Ethyl-4-chlorofluorobenzene; 2-Fluoro-5-chloroethylbenzene; 4-Chloro-2-ethylfluorobenzene; 1-Fluoro-2-ethyl-4-chlorobenzene; (4-Chloro-2-ethylphenyl)fluoride
EINECS	Contact for details

Quality Control

Our Benzene, 4-Chloro-2-Ethyl-1-Fluoro- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.