Description

1-Bromo-3-Isopropoxy-5-(Trifluoromethyl)Benzene is a high-purity aromatic building block designed for advanced organic synthesis. This compound is valued for its unique trifluoromethyl and bromo substituents, which are critical for modulating the electronic and steric properties of target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to construct complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.
• Ligand and Catalyst Development: Used to synthesize sophisticated ligands for catalysis or as a structural component in organometallic catalysts.

Basic Information

Product Name	1-Bromo-3-Isopropoxy-5-(Trifluoromethyl)Benzene
CAS No.	1369784-85-9
Molecular Formula	C10H10BrF3O
Molecular Weight	283.09 g/mol
Synonyms	3-Bromo-1-isopropoxy-5-(trifluoromethyl)benzene; 1-Bromo-3-isopropoxy-5-(trifluoromethyl)benzene; 5-Bromo-1-isopropoxy-3-(trifluoromethyl)benzene; Benzene, 1-bromo-3-(1-methylethoxy)-5-(trifluoromethyl)-; 3-(1-Methylethoxy)-5-(trifluoromethyl)bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Isopropoxy-5-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.