Description

5-(tert-Butyl)-1H-Indole-3-Carbaldehyde is a versatile indole derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a reactive aldehyde group and a sterically hindered tert-butyl substituent, makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting neurological disorders, inflammation, and oncology.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Used in the creation of organic semiconductors, liquid crystals, and photochromic materials due to its electron-rich indole core.
• Chemical Synthesis: Serves as a starting material for synthesizing more complex indole alkaloids and heterocyclic compounds via condensation and cyclization reactions.
• Dye & Pigment Industry: Intermediate for producing specialized indole-based dyes and colorants.

Basic Information

Product Name	5-(tert-Butyl)-1H-Indole-3-Carbaldehyde
CAS No.	1369055-82-2
Molecular Formula	C₁₃H₁₅NO
Molecular Weight	201.27 g/mol
Synonyms	5-tert-Butyl-1H-indole-3-carboxaldehyde; 5-(1,1-Dimethylethyl)-1H-indole-3-carboxaldehyde; 3-Formyl-5-tert-butylindole; 5-tert-Butylindole-3-carbaldehyde; 5-(tert-Butyl)indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 5-(1,1-dimethylethyl)-; 5-tert-Butyl-1H-indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-(tert-Butyl)-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.