Description

(1-Trifluoromethyl-Cyclopropyl)-Acetic Acid CAS NO 1368342-07-7 is a high-value fluorinated building block characterized by its unique cyclopropyl ring and trifluoromethyl group. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty monomers and polymers, contributing to materials with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in the design of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable substrate for studying novel fluorination reactions and the properties of fluorinated cyclopropanes.

Basic Information

Product Name	(1-Trifluoromethyl-Cyclopropyl)-Acetic Acid
CAS No.	1368342-07-7
Molecular Formula	C6H7F3O2
Molecular Weight	168.11 g/mol
Synonyms	2-(1-(Trifluoromethyl)cyclopropyl)acetic acid; [1-(Trifluoromethyl)cyclopropyl]acetic Acid; 1-Trifluoromethylcyclopropaneacetic Acid; (1-(Trifluoromethyl)cyclopropyl)acetic Acid; α-Carboxy-1-trifluoromethylcyclopropane; Cyclopropaneacetic acid, 1-(trifluoromethyl)-; 1368342-07-7
EINECS	Contact for details

Quality Control

Every batch of (1-Trifluoromethyl-Cyclopropyl)-Acetic Acid is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.