Description

4-Methyl-N'-[(1E)-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methylidene]Benzene-1-Sulfono is a high-purity, advanced organic intermediate featuring a sulfonohydrazone backbone and a protected boronic acid ester functional group. This compound is engineered for precision in complex organic synthesis, offering a stable and reactive handle for cross-coupling reactions and molecular construction. It is a critical building block for researchers and manufacturers in pharmaceutical development, agrochemical research, and materials science, particularly in the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in Suzuki-Miyaura cross-coupling reactions to create biaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the boronate ester group enables efficient coupling to create complex bioactive molecules.
• Material Science & OLED Development: Serves as a building block for creating organic semiconductors, light-emitting materials, and advanced polymers with tailored electronic properties.
• Chemical Biology & Probe Synthesis: Utilized in constructing molecular probes and bioconjugates for diagnostic and research applications due to its selective reactivity.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Essential reagent for methodological development in organic chemistry and scale-up process research.

Basic Information

Product Name	4-Methyl-N'-[(1E)-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methylidene]Benzene-1-Sulfono
CAS No.	1367368-40-8
Molecular Formula	C20H24BNO4S
Molecular Weight	385.29 g/mol
Synonyms	4-Methyl-N'-[(1E)-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methylidene]benzenesulfonohydrazide; 4-Methylbenzenesulfonic acid [4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzylidene]-hydrazide; (E)-4-Methyl-N'-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylidene)benzenesulfonohydrazide; p-Toluenesulfonyl hydrazone of 4-Formylphenylboronic acid pinacol ester; Boric acid, B-[4-[(E)-[(4-methylphenyl)sulfonyl]hydrazono]methyl]phenyl]-, 1,1-dimethylethyl ester; 1367368-40-8; Sulfonohydrazone Boronate Ester
EINECS	Contact for details

Quality Control

Our 4-Methyl-N'-[(1E)-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methylidene]Benzene-1-Sulfono is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for demanding research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.