Description

8-Methylquinoline-5-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators with enhanced properties.
• Material Science: Serves as a precursor for organic electronic materials, including OLEDs and conductive polymers.
• Chemical Research & Development: A versatile reagent for academic and industrial labs exploring new C-C bond formation methodologies.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Integral to the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	8-Methylquinoline-5-Boronic Acid Pinacol Ester
CAS No.	1366740-47-7
Molecular Formula	C₁₇H₂₂BNO₂
Molecular Weight	283.18 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-8-methylquinoline; 8-Methylquinolin-5-ylboronic acid pinacol ester; 8-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; Quinoline-5-boronic acid pinacol ester, 8-methyl-; 1366740-47-7; 8-Methyl-5-quinolineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 8-Methylquinoline-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.