Description

2-(4-Cyclopropylmethoxyphenyl)-4,4,5,5-Tetramethyl[1,3,2]Dioxaborolane is a high-value organoboron building block, specifically a pinacol boronic ester, critical for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery, crop protection agent development, and organic electronic material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the 4-cyclopropylmethoxyphenyl moiety for therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Serves as a building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) with tailored electronic or structural properties.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and tags for studying biological processes and target engagement.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds with high efficiency and functional group tolerance.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis organizations serving the life sciences industry.

Basic Information

Product Name	2-(4-Cyclopropylmethoxyphenyl)-4,4,5,5-Tetramethyl[1,3,2]Dioxaborolane
CAS No.	1366577-88-9
Molecular Formula	C₁₆H₂₃BO₃
Molecular Weight	274.17 g/mol
Synonyms	4-Cyclopropylmethoxyphenylboronic acid pinacol ester; (4-(Cyclopropylmethoxy)phenyl)boronic acid pinacol ester; 2-[4-(Cyclopropylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(Cyclopropylmethoxy)benzeneboronic acid pinacol ester; CPMPB Pinacol Ester; 1366577-88-9 (CAS); 2-(4-(Cyclopropylmethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(4-Cyclopropylmethoxyphenyl)-4,4,5,5-Tetramethyl[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for demanding research and scale-up applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.