Description

4-[3-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Morpholine is a high-purity, synthetically valuable boronic ester derivative. This compound matters as a critical advanced pharmaceutical intermediate and versatile building block in modern organic synthesis, particularly for cross-coupling reactions. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl groups, essential for synthesizing complex molecules.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, light-emitting materials, and advanced polymers.
• Chemical Biology & Probe Development: Useful for creating bioconjugates and molecular probes for diagnostic and research applications.
• Scale-up & Process Chemistry: Suitable for transitioning from laboratory-scale discovery to pilot and commercial-scale manufacturing.

Basic Information

Product Name	4-[3-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Morpholine
CAS No.	1366131-51-2
Molecular Formula	C17H26BNO4
Molecular Weight	319.21 g/mol
Synonyms	4-(3-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholine; 2-(4-Morpholino-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxyphenyl)morpholine; CAS 1366131-51-2; Pinacol ester of 4-(4-Morpholino-2-methoxyphenyl)boronic acid; 4-Morpholinophenylboronic acid pinacol ester derivative.
EINECS	Contact for details

Quality Control

Our 4-[3-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Morpholine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.