Description

2-(6-Isobutoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity naphthalene-based boronic ester, a critical intermediate in modern synthetic organic chemistry. Its primary value lies in enabling efficient, selective cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery, ligand synthesis, and the development of organic electronic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require complex aryl-aryl bond formations.
• Material Science & OLEDs: Serves as a precursor for creating organic light-emitting diode (OLED) materials, liquid crystals, and conductive polymers.
• Chemical Research & Development: An invaluable tool for academic and industrial chemists exploring new synthetic pathways and creating novel organic compounds.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and pigments where specific aromatic structures are required.

Basic Information

Item	Details
Product Name	2-(6-Isobutoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	1363386-57-5
Molecular Formula	C20H27BO3
Molecular Weight	326.24 g/mol
Synonyms	2-(6-(Isobutoxy)naphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(6-Isobutoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Isobutoxy-2-naphthaleneboronic acid pinacol ester; (6-(Isobutoxy)naphthalen-2-yl)boronic acid pinacol ester; PINACOL 2-(6-ISOBUTOXY-2-NAPHTHYL)BORONATE
EINECS	Contact for details

Quality Control

Every batch of 2-(6-Isobutoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive cross-coupling applications. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC/NMR), assay, and impurity profiles is provided with each shipment to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.