Description

6-Iodo-2-Oxa-Spiro[3.3]Heptane is a high-value, specialized spirocyclic building block featuring a reactive iodo substituent. This compound is critical for medicinal chemistry and advanced materials research, enabling the efficient construction of complex, three-dimensional molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery and the synthesis of novel functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disease targets.
• Medicinal Chemistry: Used in fragment-based drug discovery and lead optimization to introduce spirocyclic scaffolds, improving drug-like properties such as solubility and metabolic stability.
• Cross-Coupling Reactions: Serves as an electrophilic coupling partner in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to form new carbon-carbon bonds.
• Agrochemical Research: Employed in the development of new generation herbicides and pesticides with novel modes of action.
• Material Science: A precursor for synthesizing functionalized polymers and organic electronic materials with specific optoelectronic properties.
• Chemical Biology: Used as a probe or labeling agent in bioconjugation and target identification studies.

Basic Information

Item	Details
Product Name	6-Iodo-2-Oxa-Spiro[3.3]Heptane
CAS No.	1363381-15-0
Molecular Formula	C6H9IO
Molecular Weight	224.04 g/mol
Synonyms	6-Iodo-2-oxaspiro[3.3]heptane; 2-Oxa-6-iodaspiro[3.3]heptane; 6-Iodospiro[3.3]heptan-2-one, oxime?; Iodospirocyclic ether; Spiro[3.3]heptane, 6-iodo-2-oxa-; 1363381-15-0; Building block 1363381-15-0
EINECS	Contact for details

Quality Control

Every batch of 6-Iodo-2-Oxa-Spiro[3.3]Heptane is produced and tested under strict quality management protocols to ensure consistency and reliability for research and scale-up. Our products undergo rigorous quality testing, including advanced chromatographic analysis, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.