Description

tert-Butyl (2-Azaspiro[4.5]Decan-7-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Protease Inhibitor Synthesis: The spirocyclic amine core is valuable for creating inhibitors targeting specific enzymes.
• Ligand and Receptor Modulator Development: Employed in the synthesis of molecules designed to interact with G-protein-coupled receptors (GPCRs) and other biological targets.
• Chemical Biology Probes: Serves as a starting material for creating tools to study biological pathways and mechanisms of action.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials.

Basic Information

Product Name	tert-Butyl (2-Azaspiro[4.5]Decan-7-Yl)Carbamate
CAS No.	1363381-13-8
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	Boc-2-Azaspiro[4.5]decan-7-amine; 7-((tert-Butoxycarbonyl)amino)-2-azaspiro[4.5]decane; 2-Azaspiro[4.5]decan-7-amine, N-Boc-protected; tert-Butyl 2-azaspiro[4.5]decan-7-ylcarbamate; 7-(Boc-amino)-2-azaspiro[4.5]decane; N-Boc-2-azaspiro[4.5]decan-7-amine; 2-Azaspiro[4.5]decan-7-amine, 1,1-dimethylethyl carbamate (9CI)
EINECS	Contact for details

Quality Control

Our tert-Butyl (2-Azaspiro[4.5]Decan-7-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.