Description

2-(2-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing cyclopropyl and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aromatic coupling.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	2-(2-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1362243-53-5
Molecular Formula	C15H21BO2
Molecular Weight	244.14 g/mol
Synonyms	2-(2-Cyclopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Cyclopropylphenyl)boronic acid pinacol ester; 2-Cyclopropylphenylboronic acid pinacol ester; 2-Cyclopropylbenzeneboronic acid pinacol ester; (2-Cyclopropyiphenyl)boronic acid pinacol ester; 2-Cyclopropylphenyl-Bpin; 2-CyclopropylphenylBPin; 2-(2-Cyclopropylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(2-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.