Description

1H-Pyrazole, 1-(Phenylmethyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who are developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for novel drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyrazole core's bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in creating molecular probes and tools for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Specifically designed as a versatile coupling partner in palladium-catalyzed Suzuki-Miyaura reactions to form carbon-carbon bonds.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global market.

Basic Information

Product Name	1H-Pyrazole, 1-(Phenylmethyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1362243-50-2
Molecular Formula	C16H23BN2O2
Molecular Weight	286.18 g/mol
Synonyms	1-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Benzyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzyl-1H-pyrazole; 1-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole; 1H-Pyrazole-5-boronic acid, 1-(phenylmethyl)-, pinacol ester; 1362243-50-2; 1-Benzyl-5-(pinacolboryl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole, 1-(Phenylmethyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.