Description

1-Methyl-3-Nitro-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyridin-2-One is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in its role as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used to create complex heterocyclic structures found in advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for developing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodology development and exploring new synthetic pathways in academic and industrial R&D laboratories.
• Scale-up & Process Chemistry: Suitable for process optimization and pilot-scale synthesis of target molecules requiring this specific boronic ester functionality.

Basic Information

Product Name	1-Methyl-3-Nitro-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyridin-2-One
CAS No.	1361941-27-6
Molecular Formula	C12H17BN2O5
Molecular Weight	280.09 g/mol
Synonyms	1-Methyl-3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-3-nitro-1,2-dihydropyridin-2-one; 1-Methyl-3-nitro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyridin-2-one; 1361941-27-6; 2(1H)-Pyridinone, 1-methyl-3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1-Methyl-3-nitro-5-(pinacolatoboryl)-1H-pyridin-2-one
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-Nitro-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyridin-2-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.