Description

6-(Trifluoromethoxy)Pyridine-2-Carbaldehyde is a versatile and high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethoxy-substituted pyridine core offers enhanced lipophilicity and metabolic stability, making it indispensable for creating novel molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can improve biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for designing molecular probes and tags due to its reactive aldehyde group, enabling bioconjugation.

Basic Information

Product Name	6-(Trifluoromethoxy)Pyridine-2-Carbaldehyde
CAS No.	1361692-57-0
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	2-Formyl-6-(trifluoromethoxy)pyridine; 6-(Trifluoromethoxy)-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 6-(trifluoromethoxy)-; 6-Trifluoromethoxypyridine-2-carbaldehyde; 6-(Trifluoromethoxy)picolinaldehyde
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethoxy)Pyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.