Description

Cyclobutylboronic Acid Pinacol Ester is a high-purity organoboron reagent, a key building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, facilitating the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for constructing cyclobutyl-containing scaffolds in drug discovery and development programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides with cyclobutyl motifs.
• Material Science: Serves as a precursor for creating advanced polymers and organic electronic materials with tailored properties.
• Suzuki-Miyaura Cross-Coupling: The primary application, enabling the efficient formation of C-C bonds between the cyclobutyl group and various aryl/heteroaryl halides or triflates.
• Ligand and Catalyst Development: Utilized in the preparation of novel boron-containing ligands for catalytic systems.
• Academic & Process R&D: A valuable tool for methodological studies and scaling up synthetic routes in laboratory and pilot plant settings.

Basic Information

Product Name	Cyclobutylboronic Acid Pinacol Ester
CAS No.	1360914-08-4
Molecular Formula	C10H19BO2
Molecular Weight	182.07 g/mol
Synonyms	Cyclobutylboronic Acid Pinacol Ester; 4,4,5,5-Tetramethyl-2-cyclobutyl-1,3,2-dioxaborolane; 2-Cyclobutyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Cyclobutyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Cyclobutylboronic Acid, Pinacol Ester; Cyclobutyl Pinacol Boronate; CyclobutylBPin; Cyclobutyl-BPin
EINECS	Contact for details

Quality Control

Our Cyclobutylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.