Description

[4-[Bis(4-Chlorophenyl)Methyl]Piperazin-1-Yl]-(5-Methyl-4-Nitro-1,2-Oxazol-3-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates, ensuring process consistency and regulatory compliance from early development to scale-up.

Application

This specialized intermediate is designed for advanced synthetic chemistry applications, primarily serving the pharmaceutical and agrochemical research sectors.

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) or anti-infective targets.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its nitro-isoxazole and chlorinated biphenylmethyl piperazine motifs.
• Chemical Biology & Proteomics: Acts as a scaffold or linker molecule in the design of chemical probes for studying enzyme function and protein-protein interactions.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or optical properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations conducting custom synthesis and process optimization for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	[4-[Bis(4-Chlorophenyl)Methyl]Piperazin-1-Yl]-(5-Methyl-4-Nitro-1,2-Oxazol-3-Yl)Methanone
CAS No.	1360705-96-9
Molecular Formula	C22H20Cl2N4O4
Molecular Weight	475.33 g/mol
Synonyms	4-[(4,4'-Dichlorodiphenyl)methyl]-1-piperazinyl(5-methyl-4-nitro-3-isoxazolyl)methanone; (5-Methyl-4-nitro-1,2-oxazol-3-yl){4-[(4-chlorophenyl)(4-chlorophenyl)methyl]piperazin-1-yl}methanone; 1360705-96-9; 4-[(Bis(4-chlorophenyl)methyl]-1-piperazinyl (5-methyl-4-nitro-3-isoxazolyl) methanone; UNII-8K8V1168Y6; 8K8V1168Y6; SCHEMBL23306277.
EINECS	Contact for details

Quality Control

Our production of [4-[Bis(4-Chlorophenyl)Methyl]Piperazin-1-Yl]-(5-Methyl-4-Nitro-1,2-Oxazol-3-Yl)Methanone adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with research-grade and GMP-starting material standards where applicable. Certificates of Analysis (COA) detailing batch-specific results are provided and traceability is maintained for all materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants. Do not store near heat or open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.