Description

(4-Fluorothiophen-2-Yl)Boronic Acid is a high-purity organoboronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the valuable 4-fluorothiophene moiety into target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate fluorinated heterocycles for enhanced efficacy.
• Material Science Research: Serves as a precursor for synthesizing functionalized polymers, organic semiconductors, and liquid crystals for electronic applications.
• Chemical Biology & Diagnostics: Employed in the synthesis of probes, tags, and linker molecules for bioconjugation and assay development.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to create biaryl and heterobiaryl structures with high efficiency and selectivity.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	(4-Fluorothiophen-2-Yl)Boronic Acid
CAS No.	1360465-66-2
Molecular Formula	C4H4BFO2S
Molecular Weight	145.95 g/mol
Synonyms	2-(4-Fluorothiophen-2-yl)boronic acid; (4-Fluoro-2-thienyl)boronic acid; 4-Fluorothiophene-2-boronic acid; 4-Fluoro-2-thiopheneboronic acid; (4-Fluorothiophen-2-yl)boronic acid; 2-Borono-4-fluorothiophene; 4-Fluoro-2-thienylboronic acid; 4-Fluorothien-2-ylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of (4-Fluorothiophen-2-Yl)Boronic Acid is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.