Description

4,4,5,5-Tetramethyl-2-[4-(4-Methylphenoxy)Phenyl]-1,3,2-Dioxaborolane CAS NO 1358754-78-5 is a high-purity, advanced boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile and stable coupling partner in cross-coupling reactions, enabling the efficient construction of complex organic frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of functional organic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common motif in active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in constructing complex aromatic and heteroaromatic systems.
• Agrochemical Synthesis: Employed in creating advanced active ingredients for crop protection products, leveraging its stability and reactivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Organic Light-Emitting Diodes (OLEDs): A building block for the synthesis of charge-transporting or emissive materials used in display and lighting technologies.
• Polymer Chemistry: Can be incorporated into polymer backbones or as an end-group for functional polymers via controlled polymerization techniques.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[4-(4-Methylphenoxy)Phenyl]-1,3,2-Dioxaborolane
CAS No.	1358754-78-5
Molecular Formula	C19H23BO3
Molecular Weight	310.20 g/mol
Synonyms	[4-(4-Methylphenoxy)phenyl]boronic acid pinacol ester; 4-(4-Methylphenoxy)benzeneboronic acid pinacol ester; 2-[4-(4-Methylphenoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(p-Tolyloxy)phenylboronic acid pinacol ester; Pinacol [4-(4-methylphenoxy)phenyl]boronate; 4-(4-Methylphenoxy)phenyl-Bpin
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[4-(4-Methylphenoxy)Phenyl]-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to relevant industry standards and can support development projects requiring specific analytical protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent hydrolysis. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.