Description

Potassium 3-(3-Methylpiperidin-1-Yl)Prop-1-En-2-Yltrifluoroborate is a specialized organotrifluoroborate salt, a highly valuable class of reagents in modern synthetic chemistry. This compound is particularly significant as a stable, air- and moisture-tolerant precursor for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing the 3-methylpiperidine moiety.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable organoboron reagent for palladium-catalyzed cross-coupling with aryl or vinyl halides, facilitating the introduction of complex alkenyl-piperidine fragments.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Ligand and Catalyst Synthesis: Employed in the preparation of sophisticated nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: A precursor for creating functionalized polymers or organic electronic materials with tailored properties.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or molecular probes for biological target identification and validation.

Basic Information

Product Name	Potassium 3-(3-Methylpiperidin-1-Yl)Prop-1-En-2-Yltrifluoroborate
CAS No.	1357559-58-0
Molecular Formula	C9H15BF3KN
Molecular Weight	250.13 g/mol
Synonyms	Potassium (E)-3-(3-Methylpiperidin-1-yl)prop-1-en-2-yltrifluoroborate; Potassium (1-(3-Methylpiperidin-1-yl)allyl)trifluoroborate; Potassium Trifluoro((E)-1-(3-methylpiperidin-1-yl)allyl)borate; (E)-Potassium 3-(3-Methyl-1-piperidinyl)-1-propen-2-yltrifluoroborate; Potassium (E)-1-(3-Methylpiperidin-1-yl)allyltrifluoroborate; K-Org-BF3 Salt; Organotrifluoroborate Reagent 1357559-58-0
EINECS	Contact for details

Quality Control

Our Potassium 3-(3-Methylpiperidin-1-Yl)Prop-1-En-2-Yltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity for demanding synthetic applications. Each lot is characterized by NMR (1H, 13C, 11B, 19F), HPLC, and elemental analysis to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic (moisture-sensitive) nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isomeric Purity (E/Z ratio)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.