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2,5-Dichloro-3-Methoxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine CAS NO 1357387-52-0


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CAS No.:1357387-52-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,5-Dichloro-3-Methoxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and organic electronics industries who require precise and reliable intermediates for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
  • Agrochemical Synthesis: Used to construct novel pyridine-based herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
  • Material Science: Building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) used in electronic devices and sensors.
  • Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry, facilitating rapid exploration of chemical space and scale-up of target molecules.
  • Ligand Synthesis: Intermediate for the preparation of sophisticated ligands used in catalysis and coordination chemistry.

Basic Information

Product Name 2,5-Dichloro-3-Methoxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No. 1357387-52-0
Molecular Formula C13H17BCl2NO3
Molecular Weight 316.00 g/mol
Synonyms 2,5-Dichloro-3-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dichloro-3-methoxypyridine; 2,5-Dichloro-3-methoxypyridine-6-boronic acid pinacol ester; Pyridine, 2,5-dichloro-3-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; CAS 1357387-52-0
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Quality Control

Our 2,5-Dichloro-3-Methoxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, purity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed under an inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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