Description

n-(Prop-2-Yn-1-Yl)-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a specialized organic compound featuring a benzamide core functionalized with a propargyl group and a pinacol boronate ester. This structure makes it a valuable high-purity building block for advanced synthesis, particularly in pharmaceutical research and materials science. It is primarily utilized by R&D chemists and process development scientists in the life sciences and fine chemical industries who require precise, reliable intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring Suzuki-Miyaura cross-coupling reactions.
• Organic Synthesis Building Block: Used in medicinal chemistry for the introduction of boronic ester and alkyne functional groups, enabling further derivatization and library synthesis.
• Agrochemical Research: Serves as an intermediate in the development of novel crop protection agents and herbicides.
• Material Science: Employed in the research and development of organic electronic materials, polymers, and ligands for catalysis.
• Bioconjugation Chemistry: The alkyne moiety allows for use in click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), for labeling and bioconjugation applications.

Basic Information

Product Name	n-(Prop-2-Yn-1-Yl)-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	1357387-28-0
Molecular Formula	C17H22BNO3
Molecular Weight	299.18 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(prop-2-yn-1-yl)benzamide; N-Propargyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 3-(Pinacolatoboryl)-N-(2-propynyl)benzamide; Benzamide, N-(2-propynyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1357387-28-0; BRN 28246395
EINECS	Contact for details

Quality Control

Our n-(Prop-2-Yn-1-Yl)-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.