Description

2-(5-Methoxy-2-Nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for target identification and biomarker studies.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in cross-coupling chemistry and novel synthetic route exploration.
• Liquid Crystal & Polymer Chemistry: Intermediate for synthesizing monomers and functional units that impart specific optical or mechanical properties to advanced polymers.

Basic Information

Product Name	2-(5-Methoxy-2-Nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.	1356943-81-1
Molecular Formula	C13H18BNO5
Molecular Weight	279.10 g/mol
Synonyms	5-Methoxy-2-nitrophenylboronic acid pinacol ester; (5-Methoxy-2-nitrophenyl)boronic acid pinacol ester; 2-Nitro-5-methoxyphenylboronic acid pinacol ester; Pinacol (5-methoxy-2-nitrophenyl)boronate; 2-(5-Methoxy-2-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methoxy-2-nitrobenzeneboronic acid pinacol ester; CAS 1356943-81-1
EINECS	Contact for details

Quality Control

Our 2-(5-Methoxy-2-Nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.