Description

3-Benzyloxyphenylboronic Acid Mida Ester is a high-value, protected boronic acid derivative designed for advanced synthetic chemistry. This compound is crucial for enabling robust, iterative cross-coupling reactions, offering superior stability and handling compared to its free boronic acid counterpart. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the efficient synthesis of complex molecules and building blocks.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Chemical Biology & Probe Development: Enables the site-specific labeling and modification of biomolecules due to its selective reactivity profile.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries in medicinal chemistry programs.
• Process Chemistry & Scale-up: Its enhanced stability makes it suitable for multi-step synthesis and larger-scale manufacturing processes.

Basic Information

Product Name	3-Benzyloxyphenylboronic Acid Mida Ester
CAS No.	1356823-23-8
Molecular Formula	C₁₆H₁₆BNO₄
Molecular Weight	297.12 g/mol
Synonyms	3-(Benzyloxy)phenylboronic acid MIDA ester; N-Methyliminodiacetic acid (3-benzyloxyphenyl)boronate; B-(3-(Benzyloxy)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane-4,6-dione (MIDA boronate analog); 3-Benzyloxybenzeneboronic acid MIDA ester; 3-(Phenylmethoxy)benzeneboronic acid MIDA ester; Boronic acid, B-[3-(phenylmethoxy)phenyl]-, 2,2'-(methylimino)diacetic acid ester; MIDA Boronate of 3-Benzyloxybenzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Benzyloxyphenylboronic Acid Mida Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee batch-to-batch consistency and support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.