Description

2-Methyl-5-Trifluoromethylpyridine-3-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its molecular architecture, featuring both a pyridine core and a protected boronic acid group, makes it a critical intermediate for constructing complex heterocyclic compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used to create advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a building block for developing organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic Research: Utilized in university and institutional labs for methodological development in organometallic chemistry and catalysis.

Basic Information

Product Name	2-Methyl-5-Trifluoromethylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1356579-72-0
Molecular Formula	C13H17BF3NO2
Molecular Weight	287.09 g/mol
Synonyms	2-Methyl-5-(trifluoromethyl)pyridine-3-boronic acid pinacol ester; (2-Methyl-5-(trifluoromethyl)pyridin-3-yl)boronic acid pinacol ester; 3-Pyridineboronic acid, 2-methyl-5-(trifluoromethyl)-, 1,1-dimethylethyl ester; 2-Methyl-5-trifluoromethyl-3-pyridylboronic acid pinacol ester; Pinacol [2-methyl-5-(trifluoromethyl)pyridin-3-yl]boronate; B-[2-Methyl-5-(trifluoromethyl)-3-pyridinyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container should be allowed to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.