Description

Potassium Cyclopypropylmethyltrifluoroborate (CAS NO 1356481-57-6) is a high-value organoboron reagent, specifically a potassium trifluoroborate salt, prized for its enhanced stability and handling properties compared to traditional boronic acids. This compound serves as a critical coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the cyclopropylmethyl moiety in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides that incorporate cyclopropane rings for enhanced biological activity.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable, air- and moisture-tolerant organoboron reagent for palladium-catalyzed C-C bond formation.
• Material Science: Employed in the creation of organic electronic materials and liquid crystals where the cyclopropane structure influences material properties.
• Medicinal Chemistry: Facilitates the exploration of structure-activity relationships (SAR) by providing a versatile handle for molecular diversification.
• Process Chemistry & Scale-up: Offers advantages in manufacturing processes due to its improved stability, supporting robust and scalable synthetic routes.

Basic Information

Item	Details
Product Name	Potassium Cyclopypropylmethyltrifluoroborate
CAS No.	1356481-57-6
Molecular Formula	C4H7BF3K
Molecular Weight	161.99 g/mol
Synonyms	Potassium (Cyclopropylmethyl)trifluoroborate; Cyclopropylmethyltrifluoroboronic Acid Potassium Salt; Potassium Cyclopropylmethyl-Trifluoroboronate; (Cyclopropylmethyl)Potassium Trifluoroborate; Cyclopropylmethyl-BF3K; K-cyclopropylmethyltrifluoroborate; Potassium Trifluoro(cyclopropylmethyl)borate
EINECS	Contact for details

Quality Control

Our production of Potassium Cyclopypropylmethyltrifluoroborate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive catalytic applications. Each lot is characterized by advanced analytical techniques including NMR (1H, 11B, 13C) and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain long-term stability. Recommended storage temperature is 2-8°C for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (NMR / Elemental Analysis)	≥ 97%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.